NLM DIR Seminar Schedule
UPCOMING SEMINARS
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Feb. 18, 2025 Samuel Lee
Efficient predictions of alternative protein conformations by AlphaFold2-based sequence association -
Feb. 25, 2025 Zhizheng Wang
GeneAgent: Self-verification Language Agent for Gene Set Analysis using Domain Databases -
March 4, 2025 Sofya Garushyants
TBD -
March 11, 2025 Sanasar Babajanyan
TBD -
March 18, 2025 MG Hirsch
TBD
RECENT SEMINARS
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Feb. 11, 2025 Po-Ting Lai
Enhancing Biomedical Relation Extraction with Directionality -
Feb. 4, 2025 Victor Tobiasson
On the dominance of Asgard contributions to Eukaryogenesis -
Jan. 28, 2025 Kaleb Abram
Leveraging metagenomics to investigate the co-occurrence of virome and defensome elements at large scale -
Jan. 21, 2025 Qiao Jin
Artificial Intelligence for Evidence-based Medicine -
Jan. 17, 2025 Xuegong Zhang
Using Large Cellular Models to Understand Cell Transcriptomics Language
Scheduled Seminars on Feb. 3, 2025
Contact NLMDIRSeminarScheduling@mail.nih.gov with questions about this seminar.
Abstract:
The etiology of human chronic diseases is not fully understood. A large proportion of genetic heritability to diseases still remains elusive. Furthermore, the identification of other layers of –omic markers, such as DNA methylation, protein, and metabolite markers, remains challenging, even though a growing body of literature supports crucial roles of relevant markers in etiology of many diseases. In this talk, Dr. Wu will talk about several integrative multi-omics (genomics, transcriptomics, methylomics, proteomics, and metabolomics) studies to identify novel susceptibility genes and biomarkers for prostate and pancreatic cancer. He will also discuss the ongoing efforts for identifying population-specific and tissue-specific biomarkers for relevant diseases across racial and ethnic diverse populations.