NLM IRP Seminar Schedule
UPCOMING SEMINARS
RECENT SEMINARS
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April 16, 2024 Jaya Srivastava
Regulatory plasticity of the human genome -
April 11, 2024 Sergey Shmakov
Comprehensive survey of the TnpB RNA-guided nucleases -
April 2, 2024 Yifan Yang
Fairness and Bias in Biomedical AI -
March 28, 2024 Joseph Schafer
Evolutionary selection of proteins with two folds -
March 26, 2024 Sanasar Babajanyan
Microbial diversity and ecological complexity emerging from environmental variation and horizontal gene transfer in a simple mathematical model
Scheduled Seminars on June 15, 2022
Contact NLM_IRP_Seminar_Scheduling@mail.nih.gov with questions about this seminar.
Abstract:
Computational analysis of sequence and structures of proteins is an effective method to decipher the biochemistry and biology of proteins. I will be presenting examples of such analysis from my past and current research, focusing on two distinct strategies that bacteria employ to combat external stress. One is a study of the Ter-dependent stress response system where I will present evidence that the ter gene products and their functional partners constitute previously underappreciated, chemical stress response and anti-viral defense systems of bacteria. The other is a study of proteins in sporulating bacteria like Bacillus that form spores to tide over stress due to nutrient starvation. I will present results from the sequence, structural and experimental analysis of some of the proteins that are important for the spore coat and cortex assembly.